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Biotech / Medical : Cancer - Side effect drugs

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To: John McCarthy who started this subject	5/18/2002 4:50:51 PM
From: John McCarthy	of 57

[2000]-[XR9576]-[P-Glycoprotein Inhibitor][Xenova Group plc] Press Releases Back to Press Releases listing Xenova Group plc: First Quarter Results 2000 and Positive Interim PK Data from XR9576/Doxorubicin Trial Slough, UK, May 11, 2000 – Xenova Group plc (London Stock Exchange: XEN; Nasdaq NM: XNVA) today announced its results for the quarter ended 31 March 2000. Q1 Highlights Multi-drug resistance modulator XR9576 successfully completes Phase IIa PK study with paclitaxel (Taxol) Research agreement signed with Brunel University for the discovery and development of novel classes of telomerase inhibitors Peter Gillett, FCA, appointed as non-executive Director and Audit Committee chair Professor Stephen B Howell, MD, appointed to Scientific Advisory Board Operating expenses decline by 50% Announced Today Positive interim pharmacokinetic data from Phase IIa XR9576/doxorubicin trials Commenting, Chief Executive Officer David Oxlade said: “Significant progress has been made in Q1, in particular with XR9576’s progress through its Phase II clinical trials and a 50% reduction in operating costs in comparison with the same period last year. The encouraging interim PK interaction data relating to the use of XR9576 with doxorubicin is similar to that we have seen earlier with paclitaxel. ” xenova.co.uk

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