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Biotech / Medical : Tularik Inc. (TLRK)

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To: keokalani'nui who wrote (228)	6/14/2002 2:49:44 AM
From: Czechsinthemail	Read Replies (1) of 598

Improvement over dox seems like a reasonable expectation either as improved efficacy or a better side effect profile or hopefully both. Going forward at a higher dosage seems predicated on being able to get more benefit without significant serious side effect. As I recall, they did discuss the shortened dose administration some during the last quarter's conference call. I can't remember the details. What did they have to say about it during the breakout session? As for the combo trial, I assumed it was in place to explore improvement provided by T67+dox over dox alone. They seem to be confident that T67 will do better than dox, though perhaps not so confident that they didn't want a backup. That was my understanding of the Ph II combo. I'm looking forward to their announcement of new IND's. Do you have any more info on PPar-g? I'm also curious if they provided more information about potential partnerships. I believe he said they were hoping to announce 1 or 2 more this year.

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