Recent progress on the anthrax front from TIGR:
The Institute for Genomic Research (TIGR) is a not-for-profit research institute based in Rockville, Maryland. TIGR, which sequenced the first complete genome of a free-living organism in 1995, has been at the forefront of the genomic revolution since the institute was founded in 1992. TIGR conducts research involving the structural, functional, and comparative analysis of genomes and gene products in viruses, bacteria, archaea, and eukaryotes – higher animals and plants.
PRESS RELEASE: What's New at TIGR
Scientists Find New Markers For Anthrax Isolates
tigr.org
Excerpt:
May 9, 2002
In a pioneering use of genomics as a tool for the forensic analysis of microbes, scientists at The Institute for Genomic Research (TIGR) in Rockville, Md., and at Northern Arizona University in Flagstaff, Az., have found new genetic markers that distinguish the Bacillus anthracis isolate that was used in last fall's bioterror attack in Boca Raton, Florida, from closely related anthrax strains.
Their findings, posted on Science Express on May 9 and scheduled for later publication in Science, demonstrate for the first time that the analysis of the genomes of microbial pathogens can be an effective method of finding new "genetic fingerprints" that can help trace the differences among almost identical strains of microbes such as anthrax. Previous genetic-marker analysis had focused on a limited number of DNA segments, rather than the entire genomic sequence.
TIGR Anthrax Sequencing -- QUESTIONS AND ANSWERS
tigr.org
Excerpt:
Q:Did TIGR find any evidence that the Florida isolate had been genetically engineered?
A: No evidence of genetic engineering was found in the Florida isolate.
and finally, be the First in your neighborhood to examine the complete plasmid sequences for Bacillus anthracis "Florida" isolate (cat A2012. Ames genotype)...
tigr.org
ncbi.nlm.nih.gov
ncbi.nlm.nih.gov |
