United States Patent 6,458,945
Stanton, Jr. , et al. October 1, 2002
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Method for analyzing polynucleotides
Abstract
The present invention relates to methods for the analysis of polynucleotides including detection of variance in nucleotide sequence without the need for full sequence determination, full sequence determination of a polynucleotide, genotyping of DNA and labeling a polynucleotide fragment during the process of cleaving it into fragments.
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Inventors: Stanton, Jr.; Vincent P. (Belmont, CA); Wolfe; Jia Liu (Winchester, MA); Kawate; Tomohiko (Cambridge, MA); Verdine; Gregory L. (Lexington, MA)
Assignee: Variagenics, Inc. (Cambridge, MA)
Appl. No.: 709596
Filed: November 9, 2000 |
