Yeast display -
Abbott Laboratories (100 Abbott Park Rd., Abbott Park, IL 60064; Tel: 847/937-6100, Fax: 847/937-1511; Website: www.abbott.com) has obtained the worldwide exclusive license to yeast display technology from the University of Illinois (UI) through acquisition of the virtual company, BioDisplay Technologies, Inc., for $7 million. The technology will become part of the antibody discovery and development technology platform of Abbott Bioresearch Center (ABC) in Worcester, Massachusetts.
Yeast display technology accelerates and enhances antibody discovery by simplifying the identification of antibodies that bind more tightly to their targets (high affinity antibodies). For many targets of antibody therapy, high antibody affinity is closely linked to therapeutic potency. Yeast display, in combination with other human antibody generating technologies, should accelerate the development of promising antibodies for clinical development. The technology was developed by former UI chemical engineering professor K. Dane Wittrup (now at the Massachusetts Institute of Technology), UI biochemistry professor David M. Kranz and their graduate students.
"We are very pleased to have acquired this cutting edge technology that will expand Abbott's unique technology platform in the development of fully human antibodies by bringing viable drug candidates to the pipeline faster, leading to more effective therapies for patients," says Robert Kamen, divisional vice president of pharmaceutical discovery, Abbott Laboratories, and president of ABC...
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Limited Use Label License No. 88: Yeast Display Expression Kit
The Yeast Display Expression Kit is covered by filed US Patent Applications and is sold under license from The Board of Trustees of the University of Illinois for life science research only; not for any diagnostic, therapeutic or commercial purposes other than (d) and (e) below for evaluation for one (1) year following the date of purchase of the Expression Kit. The Expression Kit, or the materials contained therein, may not be used for any commercial purpose without a license for such purposes from The Board of Trustees of the University of Illinois, Urbana, Illinois.
Commercial purposes include: (a) Any use of Expression Products in a Commercial Product; (b) Any use of Expression Products in the manufacture of a Commercial Product; (c) Any sale of Expression Products; (d) Any use of Expression Products or the Expression Kit to facilitate or advance any research or development of a Commercial Product; and (e) Any use of Expression Products or the Expression Kit to facilitate or advance any research or development program the results of which will be applied to the development of Commercial Products.
"Expression Product(s)" means products expressed with or through use of the Expression Kit, or with or through the use of any vectors or host strains in the Expression Kit. "Commercial Product(s)" means any product intended for sale or commercial use.
Commercial entities may use this Expression Kit for the commercial purposes specified in (d) and (e) above solely for the evaluation of possible commercial applications and only for a period of one (1) year from the date of purchase of the Expression Kit, during which time they must contact the University of Illinois regarding a commercial license for use of the Expression Kit for commercial purposes, or thereafter immediately terminate their use of, and destroy any remaining components of, the Expression Kit, and so notify the University of Illinois in writing.
Access to the Expression Kit must be limited solely to those officers, employees and students of your institution who need access to perform the above-described research or evaluation. You may not distribute the Expression Kit or the vectors or host strains contained in it, nor modifications or alterations thereof, to others, even those within your own institution, without prior written approval from the University of Illinois.
Failure to comply with these terms and conditions of use shall result in immediate termination of your limited right to use the Expression Kit and you must destroy all Expression Kits in your control, and so notify Invitrogen Corporation in writing.
For information regarding commercial licenses, contact: University of Illinois, Research and Technology Management Office, Fourth Floor, Swanlund Building, 601 East John Street, Champaign, IL 61820. Tel: (217) 333-7862, Fax: (217) 244-3716.... |
