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Biotech / Medical : Biotech Valuation
CRSP 55.44-2.7%11:15 AM EST

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To: Bob L who wrote (7551)12/19/2002 3:05:29 PM
From: Vector1  Read Replies (1) of 52153
 
Bob, no question MDS should be followed. However, MDS is generally associated with both radiation and chemotherapy. Anything that comparomised the marrow. The interesting fact on the MDS incidence in Bex patients it that it only occured in the very long term reponders (over 5 years). All these patients had been through numerous chemo regimes before bex and would have been expected to have higher rates of AML. In addition it is likely that all these patients would not have survived long enough to get AML without Bex. It will be interesting to see the long term data with Zev as well although there has not been much of a record of very long term responders. One would think that Y which tends to settle in the marrow would result in greater incidence of AML but only time and long term studies will tell.

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