GUMM - Eliminate the Common Cold Message Board

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Biotech / Medical : GUMM - Eliminate the Common Cold

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To: DanZ who wrote (4194)	1/7/2003 2:27:51 PM
From: Hank	Read Replies (1) of 5582

"Assuming a treatment effect size of 30% and significance level of a = 0.05, the power to detect a significant difference between both groups with 80 total subjects was 70%." Bullshit. You only have an effective sample population of 18 people because that is the number that were confirmed to have a rhinoviral infection- not 80. The data on the rest of the subjects is invalid because you can not positively define the cause of the symptoms you are measuring. Hence, you can not account for possible differences in symptom duration that may be inherent in different causative agents. Now throw in the fact that there over 200 types of rhinoviruses and things become even less clear. The maximum number of rhinoviral serotypes that could have been tested based on the confirmed number of rhinoviral infections is 18, or a maximum theoretical 9% of the total number of rhinoviruses known to cause cold symptoms. Of course, it's highly unlikely that we're talking about the maximum here since it's extremely unlikely that each of 18 subjects had different viruses. But hey look on the bright side. Their TV ads are better than they were.

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