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Biotech / Medical : ABTI Alpha-Beta Technology

ABTI 0.200

+99,900.0%

Jun 17 12:34 PM EST

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To: Cacaito who wrote (324)	7/29/1997 2:30:00 PM
From: Cacaito	of 572

clynx.com Good review of (Betafectin). Please check the paragraph: "Although serious infections occurred less frequently in recipients of high dose pgg-glucan (1 or 2mg/kg)compared with placebo and low dose pgg-glucan 0.1 mg recipients (1 vs 4 and 3) the difference was not significant". Notice the patients were combined in two groups (initially 4 groups) to show a "trend" . They showed only a trend! Not a statistical significance. Even if they show statistical significance in the upcoming results, they will also need to show clinical and financial significance (the 3 factors do not necessarily go together). Combining groups after the results is not a good way to prove a hypothesis, especially with very small number of patients. I recognized that there are 40 hospitals involved in the ongoing study, and this is an accomplishment on itself, will assure an appropriate number of patients on a timely basis, and shows a very serious effort from the clinicians and the company involved.

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