SARS Coronavirus Sequencing
cdc.gov
April 13, 2003, 4:00 PM ET
The CDC coronavirus sequencing team has completed and assembled 17.5 kilobases of nucleotide sequence of the Urbani strain of SARS associated coronavirus. These sequences represent all of the genome except for the 1a region of the polymerase gene. The availability of this sequence provides important information relating to rapid diagnosis, treatment, and prevention of SARS. The complete genome of the Urbani strain should be available on Monday, April 14, 2003.
It should be noted that analysis of sequences from three different regions of the genome confirm the initial observation that the Urbani strain of the SARS-associated coronavirus is distinct from all previously recognized coronaviruses and sequence studies are not likely to identify a source for this novel coronavirus.
Sequence information provided by collaborators at National Microbiology Laboratory, Canada, University of California at San Francisco, Erasmus University, Rotterdam and Bernhard-Nocht Institute, Hamburg facilitated this sequencing effort.
Nucleotide Sequence of Human Coronavirus, CoV-SARS PDF (Apr 13, 2003, 4:00 PM ET)
cdc.gov
Coronavirus Protein Analysis Phylogenetic Trees PDF (Apr 13, 2003, 4:00 PM ET)
cdc.gov |
