United States Patent Application 20030054348
Kind Code A1
Blume, Arthur J. ; et al. March 20, 2003
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Methods of identifying the activity of gene products
Abstract
Methods are disclosed for determining the activity and function of gene products based on their change to the phenotype of cells when contacted with a surrogate molecule identified through screening of a recombinant peptide library. By identifying peptides which bind gene products for which the function is not yet known, tools are provided for determining their function and obtaining drug candidates.
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Inventors: Blume, Arthur J.; (Annandale, NJ) ; Goldstein, Neil; (Maplewood, NJ) ; Pillutla, Renuka; (Bridgewater, NJ) ; Hsiao, Ku-Chuan; (Easton, PA) ; Prendergast, John; (Lawrenceville, NJ)
Correspondence Name and Address: MORGAN & FINNEGAN, L.L.P.
345 Park Avenue
New York
NY
10154-0053
US
Serial No.: 852455
Series Code: 09
Filed: May 9, 2001 |
