Elmer,
First I love when Rick first take shot. So, I can choose my words more carefully. <g> ļ
Dozen indicators suggest that V will be sinergistic with chemo, and play rule in solid tumor combination(s) therapy. One good indicator (from those who are in field) is investigators and NCI entuziazm visible by V cancer trials numbers and speed they are enrolling pts and completing trials. As I mentioned early, ASCO will help to better project (at this time it is hard) V utility in other cancer type (CC, NSCLC, PS, RCC, OC, ¡K).
Do I believe that V will work. Yes, I do. But, what I believe and what is real word can be like sky and land, far, far away.
One more thing. Usually drug that work for hematology cancer does not work as good in solid tumors. Velcade may be excluded, based on mode of action. It is and will be toxic to all cells, but IF one can show me one BROAD chemo agent without toxicity I will change my mind.
Miljenko |