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Biotech / Medical : Isotechnika
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To: Icebrg who wrote (82)6/11/2003 5:35:27 AM
From: Icebrg  Read Replies (1) of 285
 
Isotechnika/Roche's ISA247 comparable to cyclosporine for kidney transplant patients

[The following is from SG Cowen's PharmaCare Update. Although the snip doesn't give any new information, it is perhaps an indication that Isotechnika's profile has been raised and that they are starting to be noticed.

Erik]

A Phase IIa study presented at the American Transplant Congress conducted by Isotechnika of the company's immunosuppressive drug ISA247 (novel calcineurin inhibitor co-developed with Roche) in stable kidney transplant patients showed that ISA247 is effective and well tolerated. Stable kidney transplant patients on ISA247 achieved a level of immunosuppression comparable to patients given cyclosporine at one third the blood drug concentration. Early studies indicate that ISA247 is onsiderably more potent and less toxic compared to other immunosuppressants, such as cyclosporine A. This powerful combination of reduced toxicity and improved potency should provide a major therapeutic benefit over existing calcineurin based regimens.
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