As far as I can see, the LSBC method doesn't infringe. the Epicyte patent covers nucleotide sequences inserted into the plant genome. LSBC are using a tobacco mosaic virus. Aren't the two things different ?
.United States Patent 5,977,438
Turpen , et al. November 2, 1999
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Production of peptides in plants as viral coat protein fusions
Abstract
The present invention relates to foreign peptide sequences fused to recombinant plant viral structural proteins and a method of their production. Fusion proteins are economically synthesized in plants at high levels by biologically contained tobamoviruses. The fusion proteins of the invention have many uses. Such uses include use as antigens for inducing the production of antibodies having desired binding properties, e.g., protective antibodies, or for use as vaccine antigens for the induction of protective immunity, including immunity against parasitic infections.
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Inventors: Turpen; Thomas H. (Vacaville, CA); Reinl; Stephen J. (Sacramento, CA); Grill; Laurence K. (Vacaville, CA)
Assignee: Biosource Technologies, Inc. (Vacaville, CA)
Appl. No.: 324003
Filed: October 14, 1994 |
