Jim,
First of all, Pennsaid is fantastic. Period. I hope we make money as investors on it.
As I understand it AIDs, Chrone's disease, Hepatitis C, and post operative systitis are all likely on the radar screen along with the long awaited fungal product.
I know that I could swing a deal to have the fungal product developed and there's no doubt the money that's there is huge. It takes many months in regimes of systemic pills with side effects to find something that works on the nail while the delivery system with the right molecule would work locally within an average of ten weeks. Phase one was done years ago proving the active ingredient penetrates all three parts of the nail and so can deliver a joint venture active ingredient effectively.
I realize sweeping statements are simplistic; however, the details here do not go that deep. I feel this is an opportunity that is being allowed to grow old on the vine.
The point of your sweeping tour is the opportunities ahead for WF10 I believe.
Let us hope that Rebecca will actually partner with at least one and hopefully two of the indications that lay before us here.
Going it alone is just too dammned hard without wads of cash, good connections, and solid experience. The WF10 patent expires between 2017 and 2018 depending on the country. That's a long time.
When we finally survive this period based on solid Canadian results - we must form a new business plan that is as much the co-ordination of the efforts of our partners on multiple fronts as it is pursuing our own interests.
It's my opinion that Canadian sales are on a curve that will top out above $20 million a year or so on a run rate somewhere around May 2005 (2 years after launch). This will equate to something around 4% of the estimated market at that time.
In the meantime there is no indication of movement on the FDA or WF10 front. I have no doubt of the hard work behind the scenes with limited cash - but I simply no longer believe in the go it alone business model for DMX.
I agree with your viewpoint on FDA if I understand it right that it will come when it comes. It's unclear why the phase III in WF10 is taking so long and we can hope that the structure that OXO chose will produce in the end a valid and useable phase III. Here I don't have any doubts about the abilities of WF10 whatever. In fact I'm quite sure WF10 will be a powerhouse.
I want to make money though and given my opinions of the reliability of reviewing bodies, I want some major pharmas driving hepatitis C for WF10 and Chrone's disease for WF10. I want to see a partnership for the fungal product if there is still value there.
A new and sensible business plan based on the core experiences gained from the last years is what's required here in my opinion. New blood would also be a good idea.
Rebecca doggedly followed the original business plan and has brought Pennsaid into north america. Mark my words that this arthritis treatment will be used by millions for a long time whether we make money off it or not.
Rebecca also brought WF10 to DMX. The potential value here dwarfs the original patents with Pennsaid.
I hold her in high esteem for her accomplishements just as I regret her cash decisions over the last 2 years and her apparent opinions about appropriate public company communication.
It would be wise now to form a new business plan that shares gains on many fronts rather than try to keep and do everything ourselves. In that I suggest speed is more important than draining the last percent.
In the meantime I don't look at it as much as I once did (sigh). I understand the possibilities surrounding cash but I don't anticipate dire events here. It's still a somewhat tense situation I think it's fair to say based on being 20% below the recent rights price - but not something IMO that won't be gotten through.
By the end of the year there will be 3 quarters in the reports (May, Aug, Nov) and the worst of this period will be ending as it becomes apparent DMX is moving steadily towards a cash neutral position.
Barring the long awaited FDA decision though, DMX simply must raise some serious extra cash. A new business plan involving partnerships in WF10 on a speedy basis is in my opinion the right move now. I suspect this has at least been on the radar - it should now be implemented I believe.
Wolf |