United States Patent 6,569,861
Bakthavatchalam , et al. May 27, 2003
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Melanin concentrating hormone receptor ligands
Abstract
Disclosed are compounds of the formula: ##STR1## and the pharmaceutically acceptable salts thereof wherein Q, X, Y, Z, and R.sub.1 R.sub.9, and R.sub.12 -R.sub.19 are defined herein. These compounds are selective modulators of MCH 1 receptors that are, therefore, useful in the treatment of a variety of metabolic, feeding, and sexual disorders. Methods of treatment of such disorders and well as packaged pharmaceutical compositions are also disclosed.
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Inventors: Bakthavatchalam; Rajagopal (Branford, CT); Thurkauf; Andrew (Danbury, CT); Hutchison; Alan (Madison, CT)
Assignee: Neurogen Corporation (Branford, CT)
Appl. No.: 900679
Filed: July 6, 2001 |
