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Biotech / Medical : Indications -- Psoriasis/Chronic Inflammation

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To: Icebrg who wrote (445)9/1/2003 5:13:21 PM
From: Icebrg  Read Replies (1) of 631
 
Fresh from the pipeline
Adalimumab

Bornadata Bain1 & Melanie Brazil2
1 Bornadata Bain is at Decision Resources Inc., 260 Charles Street, Waltham, Massachusetts 02453, USA.
2 Melanie Brazil is at Nature Reviews Drug Discovery.

Adalimumab (Humira; Abbott), an antibody that binds specifically to the inflammatory cytokine TNF-, was approved by the US FDA for the treatment of moderate to severe rheumatoid arthritis in December 2002. Does the launch of adalimumab, which is the first fully human antibody to be approved as a therapeutic, sound the death knoll for chimeric and humanized antibodies?

nature.com
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