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Biotech / Medical : XOMA. Bull or Bear?
XOMA 29.81-4.3%Dec 2 3:59 PM EST

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To: Bluegreen who wrote (16354)10/19/2003 12:50:24 PM
From: Robert K.   of 17367
 
Cytotoxic vs cytostatic......The plot thickens.....
>http://www.bloodjournal.org/cgi/content/full/96/1/176
"A novel biological activity for BPI has been reported in this study. BPI has joined the list of antiangiogenic agents that include PF4, angiostatin,22 and endostatin.23 More and more angiogenesis inhibitors are continually being discovered, and only a few will ever be used in therapeutic applications. BPI, aside from providing a potential treatment against sepsis, might also be used in the treatment of cancer and/or other angiogenesis-related pathological disorders. In its capacity as an antiangiogenic agent, BPI works specifically on and is cytotoxic to ECs, whereas both PF4 and endostatin, for example, are cytostatic, arresting ECs in the cell cycle
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