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Biotech / Medical : Kos Pharmaceuticals, Inc (KOSP)

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To: Tom D who wrote (3)	8/10/1997 9:41:00 PM
From: AARON DIDICH	of 118

TDD: Interesting thoughts on the HMO patients. On another note I don't know that Niaspan will be prescribed for stand alone therapy but will be paired with a statin. At 43 I went for a blood test and got a terrible shock with TG's in the 800's, HDL <28, CHOL>260. My cardiologist put me on Lescol 20mg QD and a diet. Cut my numbers to: 400, 25, 230 respectively. He added Niacin after 9 months in the form of Nicolar 500mg, 2 BID after breakfast and supper. Let me say it is a pain to take Niacin because of the flushing and in some cases pruritus that accompanies it. My problem is I'm an anesthesiologist and I seldom eat breakfast and I sure enjoy a cup of hot coffee(not a good idea to drink hot beverages with Niacin as it accentuates the side effects) first thing in the morning. Supper is variable too. My point is that a once daily preperation would be great for me and I am sure alot of other busy people. My cost on it is $50/100 tabs or roughly $60/mos so I am sure the average Joe would need a second mortgage to cover the tab. The IBD article suggests a price of $38/mos. so maybe the HMO's will like the option too! Do you have any insight into the hepatic sparing qualities of Niaspan? Aaron

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