GUMM - Eliminate the Common Cold Message Board

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Biotech / Medical : GUMM - Eliminate the Common Cold

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To: DanZ who wrote (4864)	11/6/2003 11:05:17 PM
From: StockDung	of 5582

Ineffectiveness of intranasal zinc gluconate for prevention of experimental rhinovirus colds. 1: Clin Infect Dis. 2001 Dec 1;33(11):1865-70. Epub 2001 Oct 25. Related Articles, Links Comment in: Clin Infect Dis. 2002 Jun 15;34(12):1657. Ineffectiveness of intranasal zinc gluconate for prevention of experimental rhinovirus colds. Turner RB. Department of Pediatrics, Medical University of South Carolina, Charleston, SC, USA. rbt2n@virginia.edu Zinc has generally been administered by the oral route in studies of prevention or treatment of the common cold. The purpose of these studies was to evaluate the effectiveness of intranasal zinc gluconate for prevention of experimental rhinovirus infection and illness. Ninety-one volunteers, 41 treated with active medication and 50 treated with placebo, received study medication for 3 days, were inoculated with rhinovirus, and then were treated with study medication for an additional 6 days. Rhinovirus infection was documented in 37 (74%) of the 50 placebo-treated volunteers and in 32 (78%) of the 41 volunteers treated with active medication. Zinc treatment had no effect on total symptom score, rhinorrhea, nasal obstruction, or the proportion of infected volunteers who developed clinical colds. These data do not support a role for intranasal zinc gluconate for prevention or treatment of the common cold. Publication Types: Clinical Trial Randomized Controlled Trial PMID: 11692298 [PubMed - indexed for MEDLINE] ncbi.nlm.nih.gov

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