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Biotech / Medical : Biotech Valuation
CRSP 56.87-2.3%Dec 5 9:30 AM EST
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To: fred hayes who wrote (9556)11/23/2003 10:39:44 PM
From: tuck  Read Replies (2) of 52153
 
Fred,

The partners walked away because it was highly probable that the unexpected incidence (however small: <0.5%) of allergic reactions would delay launch, and narrow the label and market. For PRCS, the smaller market was big enough to be worth its while. Abarelix otherwise does have a favorable side effect profile: less testosterone surge and hot flashes, and achieves medical castration faster. So even if it confers no survival benefit, it's an easier drug for patients to deal with as long as they aren't prone to those allergic reactions. I believe the new trial involved screening out such people.

I think a couple of other biofreaks may still follow PRCS; perhaps they can correct any error in detail here, as I'm going from memory. Stefaan, now back from vacation, has it in his stock picking portfolio. In any case, the label is going to be fairly important.

Cheers, Tuck
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