Xenova Group PLC
8 December 2003

                                 SCHEDULE 11

         NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS

1)   NAME OF COMPANY

     XENOVA GROUP PLC

     
2)   NAME OF DIRECTOR
                    
     a)   DAVID OXLADE
     b)   DANIEL ABRAMS
     c)   JOHN WATERFALL

3)   Please state whether notification indicates that it is in respect of
     holding of the shareholder named in 2 above or in respect of a
     non-beneficial interest or in the case of an individual holder
     if it is a holding of that person's spouse or children under the
     age of 18 or in respect of an non-beneficial interest

     AS 2 ABOVE

4)   Name of the registered holder(s) and, if more than one holder, the
     number of shares held by each of them. (If notified)

     AS 2 ABOVE....

     ...IF A DIRECTOR HAS BEEN GRANTED OPTIONS BY THE COMPANY PLEASE
                    COMPLETE THE FOLLOWING BOXES

17)  Date of grant

     5/12/2003

18)  Period during which or date on which exercisable

     3 YEAR VESTING - EXERCISABLE 5/12/2006 - 4/12/2013
     5 YEAR VESTING - EXERCISABLE 5/12/2008 - 4/12/2013

19)  Total amount paid (if any) for grant of the option

     NIL

20)  Description of shares or debentures involved: class, number.

     ORDINARY SHARES OF 10P EACH:
          
          3 YEAR          5 YEAR

     a)   450000          150000
     b)   375000          125000
     c)   300000          100000

21)  Exercise price (if fixed at time of grant) or indication that price
     is to be fixed at time of exercise

     11.25P

22)  Total number of shares or debentures over which options held
     following this notification
          
     a)   2430252
     b)   1487118
     c)   1098251...