I don't know how this will be perceived....
NEW YORK--(BUSINESS WIRE)--Aug. 14, 1997--Innovir Laboratories, Inc. (Nasdaq SmallCap: INVR.O), a company that has been developing technologies based on catalytically active oligozymes both for the treatment and prevention of diseases and also for genomic and pharmaceutical research, announced its results for the second quarter ended June 30, 1997. For the second quarter ending June 30, 1997, operating expenses were $2.6 million, as compared to $3.3 million for the same period in 1996. Expenses for the three months ended June 30, 1996 included a one time charge of $2.7 million related to the acquisition of Ribonetics GmbH in May 1996. The net loss for the second quarter of 1997 was $2.5 million, or $0.14 per share versus a net loss of $3.3 million, or $0.35 per share, for the same period in 1996. Operating expenses for the six months ending June 30, 1997 were $5.2 million, as compared to $3.9 million for the same six month period in 1996. The net loss for the six months ended June 30, 1997 was $5.0 million or $0.28 per share compared to a net loss of $3.9 million for the same six month period in 1996. Cash and short term investments at June 30, 1997, were $1.8 million versus $6.4 million at December 31, 1996. Innovir's cash position at the end of the second quarter is equal to less than one year of expenses at the current expense burn rate. The exercise of warrants by VIMRX Pharmaceuticals and The Aries Funds will provide the company with an additional $2 million. Other means of financing are being considered. Weighted average shares outstanding for the three months ended June 30, 1997 were 18.1 million versus 9.5 million for the comparable 1996 period. "We are very pleased with the progress made by the company in the first half of the year to further prove the value of the oligozyme technology to combat drug resistance and as a tool to aid target validation in drug discovery," said Allan R. Goldberg, Ph.D., President and Chief Executive Officer of Innovir.
Use of Innovir's EGS Oligozymes in Overcoming Antibiotic Resistance Receives International Attention
Dr. Sidney Altman, Sterling Professor of Biology at Yale, and his colleagues have discovered a way to use Innovir's EGS oliogozymes to convert drug-resistant bacteria to drug-sensitive by successfully eliminating the material in bacteria that prevents antibiotic drugs from exerting their toxic action on bacterial cells. Results of this study, published in the August 5th edition of Proceedings of the National Academy of Sciences, were reported by print and broadcast media in the United States and internationally. Antibiotic resistance has emerged as a major public health issue in the United States and throughout the world. The incidence of diseases once thought to be under control - such as meningitis and tuberculosis - is increasing. The reason is that over time, bacteria acquire traits that make them resistant to antibiotics. The resistant genes are passed along to other bacteria and antibiotics used to treat them become less effective. "Drug companies are investing millions of dollars to research and develop new, more powerful antibiotics to overcome drug-resistant bacteria," said Dr. Goldberg. "EGS technology represents a potential alternative approach to the problem of antibiotic resistance, one that may prove to be less expensive and time-consuming than the standard strategy of developing new drugs. Another application for this exciting technology might be the use of EGSs to treat cancer patients to overcome their resistance to certain chemotherapeutic drugs." Dr. Goldberg continued, "The technology also has the potential for broad research application by helping pharmaceutical companies to identify more effectively new genetic targets for drug development." Innovir is currently working with the pharmaceutical industry to pursue the use of oligozymes in drug discovery target validation.
Patents Issues and Allowed
During the second quarter, Innovir, in conjunction with Yale University, announced that they have been granted additional broad patent rights for a promising technology based on External Guide Sequence (EGS) oligozymes. The technology is a direct outgrowth of the work for which Dr. Altman was awarded the 1989 Nobel Prize in Chemistry. Specifically, Dr. Altman has been issued U.S. Patent No. 5,624,824, and Innovir has been allowed two additional U.S. Patent Applications - which provide comprehensive patent protection for the EGS oligozyme technology. "These patents further establish our commanding and unique competitive position in EGS oligozyme-based research and development," said Dr. Goldberg. "No intellectual property possessed by any other competitor compromises Innovir's dominant patent position in being able to fulfill this technology's extraordinary promise in therapy and research." Innovir Laboratories, Inc. (Nasdaq: INVR.O), a subsidiary of VIMRX Pharmaceuticals Inc. (Nasdaq: VMRX.O), is a biotechnology company that has been developing technologies based on catalytically interactive oligomers (oligozymes) both for the treatment and prevention of diseases and also for pharmaceutical and genomic research. As a research aid, oligozymes hold potential both to identify how different genes function and to identify and validate molecular targets for new drug therapies. The Company's technologies utilize either External Guide Sequences (EGS) oligozymes or RILON(TM) oligozymes, which inactivate targeted mRNA directly. To complement its therapeutic and drug target validation programs, Innovir has developed a unique drug delivery tool called InnoPhor(TM) that makes it possible to target oligozymes to specific tissues. The Private Securities Litigation Reform Act of 1995 provides a "safe harbor" for certain forward-looking statements. The forward-looking statements contained in this release are subject to certain risks and uncertainties. Actual results could differ materially from current expectations. Among the factors which could affect the Company's actual results and could cause results to differ from those contained in the forward-looking statements contained herein are the success of the Company's clinical trials and the development of competing therapies and/or technologies by other companies. -0- NOTE TO INVESTORS AND EDITORS: Innovir's press releases are available on the Internet through VIMRX Pharmaceutical Inc.'s web site at www.vimrx.com and through BusinessWire's web site, under the VIMRX heading, at businesswire.com. The releases also are available at no charge through Business Wire's fax-on-demand service at 800-411-8792.
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CONTACT: Laura Mastrangelo (302) 998-1734
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