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Biotech / Medical : Geron Corp.

GERN 1.490

-3.6%

2:46 PM EST

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To: r. peter Dale who wrote (124)	8/16/1997 10:27:00 PM
From: squetch	of 3578

>>A hallmark of apoptosis is fragmented DNA: that is, as a result of a cell's suicide 'program', its DNA becomes 'scrambled' into smaller pieces.<< I guess you can't tell me more about this 'scrambling'? Darci? Is this scrambling, and thus apoptosis, occuring b/c DNA repair enzymes get to far behind? Does "getting behind" lead to to much DNA damage resulting in mutation or cell death? I am not fimiliar w/ TUNEL assay. What about an assay that would measure the level of ADPRT, a DNA repair enzyme. Peter, I lurk on ARIA; thanks for your posts. squetch

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