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Biotech / Medical : Geron Corp.

GERN 1.370

0.0%

Jan 30 9:30 AM EST

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To: Tummus1 who wrote (255)	8/18/1997 1:36:00 AM
From: Nikole Wollerstein	of 3578

Somewhat puzzled by Friday runup. All this into about colocalisation of the telomerase overexpression and cancer was available for some time. Friday announcment was about gene cloning, butidentifying targets and cloning tgenes is easiest stepsin the process of drag design. To find a small molecular inhibitor, that is specific, stable, penetrate cellular andnuclear membrane - here most of them stumble. Even if GERON succeed at this stage this drug can be highly toxic due to low telomerase activity that is required for normal cell proliferation(Why this enzyme exist anyway?) Most likely if GERON succeed we will get something that increase the efficiency of radiation treatment. But they will print quite a few shares before that.

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