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Biotech / Medical : biotech binary events

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To: tuck who wrote (147)3/26/2004 1:19:12 PM
From: Icebrg  Read Replies (1) of 295
 
I used to hold NPSP, but felt I had to follow managment's example and sell the shares. There has been around 120 Form 4s filed since mid-July of last year. So, no doubt management is hedging a lot.

Amgen's AMG162 might perhaps dampen some of the "enthusiasm" surrounding Preos. (See relevant part of from the PR issued earlier this week below). Twice yearly SC injections sounds quite good.

If I remember correctly Jackson has said that they will partner if they can avoid the black box as that would make the potential market large enough to make it interesting for a big pharma partner.

Erik


AMG 162 is Amgen's fully human monoclonal antibody that specifically
targets the receptor activator of nuclear factor kappa B ligand (RANKL),
a key mediator of the body's natural pathway of the resorptive phase of
bone remodeling. Amgen is the innovator of this biologic response
modifier, one which may offer improved therapy for diseases associated
with bone loss, like osteoporosis. Intended to be administered twice-
yearly through SC injections, AMG 162 has the potential to
address key unmet patient and physician needs. Amgen presented interim
data from a Phase 2 clinical study demonstrating the clinical effect of
AMG 162 on bone endpoints. Based on preliminary clinical data, AMG 162
appears to be well-tolerated. Amgen anticipates the initiation of a Phase
3 clinical study with AMG 162 in osteoporosis in 2004.
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