AACR posters...
Sunday 8:00 AM - 12:00 PM 700 - Human antibody drug conjugates specific to the mutant EGF receptor (EGFRvIII) inhibit tumor growth observed with in vitro and in vivo models of glioma Bruce A. Keyt, Ying Liu, Francine Chen, Jean Gudas, Masahisa Handa, Ruoheng Zhang, Peter Senter, Xiao-Dong Yang. Abgenix, Fremont, CA and Seattle Genetics, Bothell, WA. Growth Factors and Antibodies in Tumor Immunotherapy Poster Session Hall B4-D, Orange County Convention Center Sunday 8:00 AM - 12:00 PM 707 - Fully human monoclonal antibodies to PSMA selectively target cytotoxins, radiotoxins and host immunity to prostate cancer Dangshe Ma, Jason P. Gardner, Christine E. Hopf, Andrew D. Malewicz, Michael A. Cohen, Gerald P. Donovan, Norbert Schülke, William F. Goeckeler, William C. Olson. The PSMA Development Company (Joint Venture between Progenics Pharmaceuticals, Inc. and Cytogen Corp.), Tarrytown, NY. Growth Factors and Antibodies in Tumor Immunotherapy Poster Session Hall B4-D, Orange County Convention Center Sunday 8:00 AM - 12:00 PM 709 - CP-675,206 anti-CTLA4 antibody clinical candidate enhances IL-2 production in cancer patient T cells in vitro regardless of tumor type or stage of disease Paul C. Canniff, Carol B. Donovan, Jeffrey J. Burkwit, Matthew J. Bruns, Vahe Bedian, Steven H. Bernstein, Douglas C. Hanson. Pfizer Global Research & Development, Groton, CT and Roswell Park Cancer Institute, Buffalo, NY. Growth Factors and Antibodies in Tumor Immunotherapy Poster Session Hall B4-D, Orange County Convention Center Tuesday 8:00 AM - 12:00 PM 3802 - Preclinical in vitro characterization of anti-CTLA4 therapeutic antibody CP-675,206 Douglas C. Hanson, Paul C. Canniff, Michael J. Primiano, Carol B. Donovan, Joseph P. Gardner, Edward J. Natoli, Rodney W. Morgan, Robert J. Mather, David H. Singleton, Paul A. Hermes, Mark J. Neveu, Glenn C. Andrews, Christopher D. Castro, Eileen A. Elliott, Vahe Bedian. Pfizer Global Research & Development, Groton, CT. Genes, Drugs, and Novel Agents Poster Session Hall B4-D, Orange County Convention Center Tuesday 1:00 PM - 5:00 PM 4566 - Secretory leukocyte protease inhibitor neutralizing fully human monoclonal antibody CR012 inhibits ovarian carcinoma cell growth in vitro Zhong Haihong, Gulshan Ara, John Macdougall, Henri H. Lichenstein, Jennifer Macaluso, Danny Chui, Francine Chen, Michael Gallo, William J. Larochelle. CuraGen Corporation, Branford, CT, Abgenix, Inc, Fremont, CA, Abgenix, Inc, Vancouver, BC, Canada. Cell and Stroma-directed New Agents Poster Session Hall B4-D, Orange County Convention Center Wednesday 8:00 AM - 12:00 PM 5347 - Generation and characterization of fully human EGFRvIII antibodies suitable for immunoconjugates Larry L. Green, Qiaojuan Jane Su, Kiran Ahluwalia, Scott L. Klakamp, Xiao-Dong Yang, Xiao Feng, Robert E. Raya, Xiao-Chi Jia, Jose R. F. Corvalan, Jean M. Gudas, Bruce A. Keyt, Ian N. Foltz, Chadwick T. King, Paul Kang, Palaniswami Rathanaswami, Orit Foord. Abgenix, Inc, Fremont, CA. Growth Factor Receptors as Therapeutic Targets Poster Session Hall B4-D, Orange County Convention Center |