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Biotech / Medical : Genta, Inc. (GNTA)

GNTA 2.300

+0.4%

Nov 7 9:30 AM EST

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To: John Nobrega who started this subject	5/4/2004 12:25:44 PM
From: Ken S.	Read Replies (2) of 1870

Art, Does this part of the company announcement refute your comment on toxicity? In a randomized clinical trial in which patients received Genasense combined with dacarbazine (n=371) compared to dacarbazine alone (n=360), the most frequent serious adverse event occurring in = 5% of patients was fever (5.9% vs. 3.1%, respectively); the most frequent Grade 3 or 4 adverse events occurring in = 5% of patients were neutropenia (21.3% vs. 12.5% respectively), thrombocytopenia (15.6% vs. 6.4%), leukopenia (7.5% vs. 3.9%), anemia (7.0% vs. 4.7%), and nausea (7.0% vs. 2.5%).

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