Here's why the telomerase gene discovery is so important for Geron: Geron has pretty much locked up the patents covering the use of telomerase inhibitors to treat cancer. Cloning the crucial telomerase gene means it's much more likely that an effective inhibitor will be developed in the not-too-distant future. In fact, Thomas Cech, the Nobel Prize winner and co-discoverer of the telomerase gene, was quoted by the NY Times as saying: "the search for a drug to test (to inhibit telomerase) would be aided by the fact that drug companies already have a large number of chemicals in their labs that in theory could interfere with telomerase. For example, several drugs used to treat AIDS, like AZT, should, even in their current formulation, inhibit telomerase production." Remember: even if Geron isn't the company that comes up with an anti-cancer telomerase inhibitor drug, they will make multi- millions anyway because they hold the critical patents. Of course, it's not certain anyone will be able to develop an effective telomerase inhibitor that will kill cancer cells. But quite a few Nobel Prize winners (including James Watson, who's on Geron's medical advisory board) think there's an excellent chance it's possible. And so does Pharmacia & Upjohn, Geron's large pharmaceutical partner. It's a reasonable assumption that P&U did their due diligence before they signed a $58 million collaborative agreement with Geron. The majority of the recent posts on this thread have been from short-term traders looking to make a quick buck. There's nothing wrong with short-term trading, but if you're a long-term biotech investor and you can take some near-term volatility, Geron is worth considering for your biotech portfolio. So, what's Geron stock worth? Biotech "guru" Michael Murphy considers Geron a core biotech holding, with a long-term target of $45. As part of their collaborative agreement with Geron, P&U purchased $2 million worth of Geron stock at $20 per share (and this was before the telomerase gene discovery). Biotech stocks are obviously hard to value, but in my view Geron's risk/reward ratio seems quite attractive at under the price P&U paid. |