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Biotech / Medical : Chromatics Color Sciences International. Inc; CCSI

CCSI 29.32

+4.6%

Oct 31 9:30 AM EST

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To: Gurupup who wrote (230)	8/21/1997 9:29:00 PM
From: Bradley W. Price	of 5736

Skip, I don't think you answered the primary question. 10 In cases of more serious hyperbilirubinemia, it is possible that this method could be useful when blood tests are not being done. However, when bilirubin is elevated enough to be considered serious, more frequent blood test to monitor liver, and kidney function would be done anyway. ___________________________________________________________________ #10 Response:"Eighteen percent of full term healthy infants are treated by phototherapy.As current discharge is occuring within 24 hours after birth,the majority of this phototherapy occurs in the home".In early hours after birth TSB tests may be done as part of a panel from cord blood. Followup tests are specifically requested for monitoring TSB and are not usually part of panels. Nearly all premature infants are monitored extensively for hyperbilirubinemia.According to MEDICAL SYSTEMS DATA STUDY "the average length of monitoring in the hospital is 11 days and the average number of TSB tests is 3 per day.The recommended treatment of phototherapy for premature infants is well under 12 mg/dl of TSB." According to American Journal for Diseases in Children,December 1992.LABORATORY EVALUATION OF JAUNDICE IN NEWBORNS,FREQUENCY,COST,"the average "hyperbilirubinemia workup" cost $125.00 per workup." Additionally,all the above are statistics related to the United States only.Other countries have the same or higher incidence as an example,the World Health Organization reports that the Asian race has a 70% incidence of bilirubin infant jaundice in all births.> As I understand it, juandice is simply a symptom. Once it is present, you have to monitor other functions. The key is that more frequent blood tests are going to be done to monitor liver and kidney function. The question is how often is that going to be done anyway every day by the prudent physician. My guess is that these tests are the primary driver behind the "number of sticks". Bottom line - I see nothing in you articles that would cause doctors to reduce the number of sticks. I know you have done a lot of research here. I am just trying to objectively evaluate the info presented. V/R Brad

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