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Biotech / Medical : Kosan BioSciences -- KOSN
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To: tuck who started this subject9/2/2004 9:47:34 AM
From: scaram(o)uche   of 933
 
eortc-nci-aacr......

woensdag 29 september 2004
Poster session: New drug targets
Poster O'Dwyer, P. 17-allylamino-17-demethoxygeldanamycin overcomes trail resistance in colon cancer cell lines
Poster Siegel, D. The role of NAD(P)H:quinone Oxidreductase 1 (NQO1) in geldanamycin, 17AAG and
17AG metabolism

woensdag 29 september 2004
Poster session: Angiogenesis and Metastasis Inhibitors
Poster Isaacs, J.S. Targeting oncogenic Eph proteins with Hsp90 inhibitors

donderdag 30 september 2004
Plenary Session 6: Proffered papers
15:15 Speaker Zaffaroni N. Silencing of survivin gene by small interfering RNAs (siRNAs) induces apoptosis in human prostate cancer cells and increases their sensitivity to 17-allylamino-17-demethoxygeldanamycin (17AAG)



donderdag 30 september 2004
Poster session: Signal transduction modulators
Poster Sherriff, M. Factors that govern the cell death response induced by inhibition of the molecular chaperone heat shock protein 90
Poster Madden, T. 17(allylamino)-17-demethoxygeldanamycin(17-AAG) suppresses tamoxifen-resistant breast cancer cell growth in vitro
Poster Eccles S.A. Key roles for HSP90 in tumour neoangiogenesis
Poster Solit, David HER2 imaging as a non-invasive pharmacodynamic marker of Hsp90 inhibition

vrijdag 1 oktober 2004
Poster session: Prodrugs
Poster Tabibi, E. In vitro release of 17-demethoxy-17-allylaminogeldannamycin
from its prodrugs
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