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Strategies & Market Trends : Booms, Busts, and Recoveries

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To: Maurice Winn who wrote (53684)9/26/2004 10:48:03 AM
From: Henry Niman  Read Replies (2) of 74559
 
Mq, The mechanism is related to cell receptors. Most avian viruses are easily passed from bird to bird, but not bird to mammal because the receptors on mammalian cells are different. Some organisms, such as pigs, can be infected by both, so there is concern that a dual infection will take some of the genetic material from the mammalian virus and put it together with the avian virus, creating a virus with an expanded host range.

Unfortunately, this has already happened.
recombinomics.com

More recent avian isolates can now more easily infect mammalian cells and this is particularly true of the isolates from Vietnam and Thailand. These viruses have some unique sequences not found in other avian viruses, but found in mammalian.

Because the avian viruses with expanded hosts ranges are endemic, more dual infections will happen, leading to more recombination.

The latest data from Thailand indicates that this may have happened recently, leading to death or symptoms in several family members.

recombinomics.com
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