On October 6, 2004, GenoMed announced that it had signed a four-year Agreement with Instituto Superiore di Sanita ("ISS") of Rome, Italy for the collaborative development of angiotesin II type 1 receptor blockers (ARB) for treatment of avian influenza type A.
GenoMed hopes the parties' collaborative research efforts under the Agreement will lead to the development of effective treatments for avian influenza Type A in chickens.
If effective ARB treatments are jointly developed by the parties under the Agreement, the parties hope to obtain a partner to commercialize the technology in the poultry production industry. Each party will retain the right to individually commercialize any treatments developed using only that party's confidential information or inventions.
As part of the Agreement, GenoMed has granted ISS the exclusive option to acquire an exclusive worldwide license, with right of sublicense, to a February 12, 2004 U.S. patent application by Dr. David W. Moskowitz, President and CEO of GenoMed, for a type of ARB treatment for birds, pigs and other vertebrate hosts, and in any further patent applications claiming priority from the same. The patent has been applied for but not issued as of the date of this report. The option will expire one year after the effective date of the Agreement. Any such license will obligate ISS to:
o pay patent prosecution expenses
o develop a research and development plan to validate the efficacy of the treatment in a statistically significant field trial program
o use efforts to identify a commercial partner
o pay GenoMed 30% of all technology transfer proceeds, after deducting patent expenses
-------------------------------------------------------------------------------- If ISS is unable to commercialize the technology within five years after exercising the option, its exclusive license would be limited to Europe, the Middle East and Africa. GenoMed would be entitled to 30% of any technology transfer proceeds in this region. There can be no assurance that any effective treatments will be developed under the Agreement, that any treatments that are developed will have commercial potential, or that the Agreement with ISS will generate revenues for GenoMed.
The Agreement prohibits either party from publishing the results of the collaboration without the consent of the other party.
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