A Biotech Bash - Recs and Wrecks Message Board

STOCKTALK

We've detected that you're using an ad content blocking browser plug-in or feature. Ads provide a critical source of revenue to the continued operation of Silicon Investor. We ask that you disable ad blocking while on Silicon Investor in the best interests of our community. If you are not using an ad blocker but are still receiving this message, make sure your browser's tracking protection is set to the 'standard' level.

Biotech / Medical : A Biotech Bash - Recs and Wrecks

Public Reply Prvt Reply Mark as Last Read File

Previous 10 Next 10 Previous Next

To: EZLibra who wrote (48)	8/27/1997 10:45:00 PM
From: r. peter Dale	of 171

Post digestion: Davis Marshall/Techniclone: Your post can serve as a paradigm for others; nice job. To a postdoc who has never been exposed to the clinical trial routine, I admit profound ignorance to even the most basic terms in this game. Could you, Rick Harmon or anyone else explain the following lingo: salvage therapy/frontline treatment; when dealing with cancer, what is the distinction between 'successfully treated' and 'complete remission' (i.e. if its not complete remission, how is the treatment 'successful'?); what time frame is used for determining complete remission (you didn't specify the cancer)? And, just so we have some it somewhere on this thread, could you provide the precise definition of Phase I, II, and III clinical trials? Do you have any advice on how to avoid getting burned by a company whose product fails at Phase III? I think I understand the TNT approach but there's no indication of what the 'innovative ...compound' is and what it identifies in the necrotic core that gives this therapy such specificity (I imagine this is a mab [monoclonal antibody] driven system). Is it TNF (tumor necrosis factor)? Can this targeting be 'retrofitted' for other diseases/tissues? And lastly, do any of the vasoactive agents involve nitric oxide? Does anyone know of companies addressing the angiogenic component of tumor development? Could the products from Techniclone not only be used to deliver drugs to the site but also to thwart or attenuate tumor development? Eric Freeman: I'll try to look at Cytogen this weekend. Could you or anyone else help out a bit and provide some more info on their SCIENCE (remember, I don't give hoot about financing, consultants and the like) - just the Science and the documented evidence (I believe I found 30+ papers when searching for 'Cytogen' - so there's lots of published data) on what they do. Rick/Baird: I've seen your Sibia thread discussion of couple of days ago. I'll return to Sibia as soon as possible. (Rick - did you get my EAEmail?) Goodnight moon Peter

Report TOU Violation

Share This Post

Public Reply Prvt Reply Mark as Last Read File

Previous 10 Next 10 Previous Next