That's what an immunologist wants to hear.
What I would expect to see, best of what can be expected from years of collected data....
a small percentage of spontaneous human cancers have the capacity to vaccinate against themselves.... most simply do not have an immunologically significant change that creates "not self".
What would I want to see, given this perspective? For trial results, large trial(s)?
I would expect (not want!) to see early survival data confounded by deaths from aggressive cancers. I'd like to see the data mature, and for long-term survivors to pop out and become the focus of additional studies. But, MOREOVER, I'd want an increased frequency of survival among the aggressive cancers, as well. I'm greedy. I'd be expecting frosting on the cake... evidence of success in the population that screwed up early results.
:-)
I have that much faith in immunization. Cellular immunologists, transplantation biologists, have thrown everything -- kitchen sink -- at T cells for decades, trying to stop them.
(any mention of long-term survivors, a nice surprise, among the g>7 population?) |
