Anyone familiar with the science behind the 11 abstracts CYTK is presenting next week ?
Sunday, December 5, 12:00 – 3:00 pm
Abstract #174: Activation of Cardiac Sarcomere ATPase by CK-1122534, a Small Molecule Agent that Specifically Targets Cardiac Myosin (Session 117, Muscle and Muscle-Associated Proteins I)
Abstract #198: Structure of Human Kip3d - Unconventional Microtubule Depolymerizing Kinesin (Session 118, Kinesin I)
Abstract #199: Regulation of ATPase Activity of Internal Motor Kinesin, pKinI: Binding to Microtubule Lattice is Non-productive (Session 118, Kinesin I)
Tuesday, December 7, 12:00 – 3:00 pm
Abstract #1480: Identification and Characterization of Candida Albicans Formins (Session 316, Actin Dynamics and Assembly II)
Abstract #1489: Regulation of WASP and N-WASP by Different Activators (Session 316, Actin Dynamics and Assembly II)
Abstract #1498: Interaction of Myosin with Blebbistatin Reported by Fluorescence Spectroscopy (Session 317, Conventional Myosin)
Abstract #1499: The Cardiac Myosin Activator, CK-1122534, Overcomes the Myosin II Inhibitors 2, 3-Butanedione-2-Monoxime and (-)-S-Blebbistatin without Affecting the Ca2+ Transient in Ventricular Myocytes (Session 317, Conventional Myosin)
Abstract #1500: The Cardiac Myosin Activator, CK-1122534, Increases Contractility in Adult Cardiac Myocytes without Altering the Calcium Transient (Session 317, Conventional Myosin)
Abstract #1501: Cellular Responses of the Myosin Activator CK-0689705 in Normal and Heart Failure Models (Session 317, Conventional Myosin)
Wednesday, December 8, 12:00 – 3:00 pm
Abstract #2128: Vasodilator-Stimulated Phosphoprotein (VASP) Promotes Arp2/3 Complex Mediated Actin Polymerization, Prevents Branching and Stabilizes Actin Filaments (Session 416, Actin Dynamics and Assembly III)
Abstract #2191: A High Throughput Screen for Inhibitors of Microtubule Depolymerizing Enzyme from Plasmodium Falciparum (Session 419, Microtubule Dynamics and Assembly II)
|
