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Pastimes : SARS - what next?
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To: Maurice Winn who wrote (963)12/13/2004 6:16:12 PM
From: Maurice Winn   of 1070
 
Speaking of vaccines, a sars vaccine trial has start. edhttp://www.halifaxlive.com/sars_vaccine_12132004_9992.php

<December 13, 2004

Trials of a vaccine developed to fight the respiratory disease SARS have started today in the US. The disease, first recognized in 2002, was responsible for more than 750 deaths around the world before being contained in 2003.

US researchers with the National Institute of Allergy and Infectious Diseases will start trials of the experimental SARS vaccine using 10 volunteers.

The initial goal of the small trial is to determine if the vaccine is safe for use in humans. The secondary goal is to determine how effective the vaccine is in fighting SARS. To do this, researchers will look for antibodies and cellular immunity stimulated by the vaccine, focusing on the SARS spike protein.

In may, researchers in China were the first to test an experimental SARS vaccine in humans. >

Let's hope the "safety" issues do not act to delay introduction of vaccines because while a vaccine might not be fully safe, the lack of protection could cost millions of lives. The FDA and medical guilds have a history of excessive control and caution resulting in high opportunity costs.

There is an over-emphasis on bureaucratic process and not enough on urgent development of life-saving treatments.

With virulent infections such as sars and humanized H5N1, the bugs can kill a billion people while the FDA dithers over some phase I safety trial which any reasonable estimate could show is unlikely to involve a significant risk.

There's a vast opportunity cost if the stable door is shut after the H5N1 bug has bolted. It's like the airlines closing the cockpit doors AFTER the 911 box-cutter hijackers bolted through and airport security people taking nail clippers from grandmothers.

Mqurice
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