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Biotech / Medical : Biotech Valuation

CRSP 55.84

+1.8%

Dec 19 9:30 AM EST

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To: zeta1961 who wrote (14732)	12/17/2004 1:49:35 PM
From: former_pgs	Read Replies (2) of 52153

>there are numerous studies using it for cancer treatment at 400-800mg/day with aggressive cancers getting 800mg.< I've long been of the opinion that the use of Celebrex in cancer was a scenario where patients were simply being used as guinea pigs. Many preclinical studies have shown that the cox-2 target of celebrex is not necessary for its anti-cancer properties. The high dosing in this population, in my opinion, was simply to capitalize on a side-effect / cross-reaction that the drug elicited to shrink intestinal polyps. These poor people may have paid the price for the experiment. Note to self: never take a drug for an indication where the drug's target has proven irrelevant. Second note to self: don't overdose on meds. :-)

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