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Biotech / Medical : Biotech Valuation
CRSP 56.71+0.4%9:30 AM EST

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To: rkrw who wrote (15081)1/4/2005 10:22:14 AM
From: Biomaven  Read Replies (1) of 52153
 
why doing modified taxol trials hasn't been very straightforward from a regulatory perspective.

In the case of APPX one issue was that their comparator was Taxol for second-line breast cancer (which is the US label), but current practice in the US is to use Taxol as first line. So they were forced to enroll overseas, mostly Eastern Europe, and also to mix first and second-line US patients.

That said, I think their drug works at least as well as Taxol if not better, and has clear tox and ease-of-use advantages over Taxol. So I guess I'd put it at better than a 50:50 shot for approval.

Anyone (rkrw?) know what the company is worth aside from Abraxane?

Peter
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