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Biotech / Medical : Biotech Valuation
CRSP 54.19-4.7%Jan 15 3:59 PM EST

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To: Biomaven who wrote (15117)1/6/2005 2:58:47 PM
From: Rudy Saucillo  Read Replies (1) of 52153
 
Curious that these studies didn't address the correlation of other known inflammation markers with CV events.

"Acute Coronary Syndrome and Inflammation. Biomarkers for Diagnostics and Risk Stratification."

ncbi.nlm.nih.gov

For example, myeloperoxidase (mentioned in the above abstract) was reduced by statistically significant amounts in the AGIX CART II treatment group. Corresponding plaque reduction in the treatment group was statistically significant w.r.t. baseline and w.r.t. SOC in the 10mm most diseased segments.

One reason CRP is studied extensively appears to be ease of measurement:

"CDC/AHA Workshop on Markers of Inflammation and Cardiovascular Disease: Application to Clinical and Public Health Practice: clinical use of inflammatory markers in patients with cardiovascular diseases: a background paper."

ncbi.nlm.nih.gov

Interestingly, myeloperoxidase is also associated with kidney disease:

"Myeloperoxidase in kidney disease"

ncbi.nlm.nih.gov

"Are advanced oxidation protein products potential uremic toxins?"

ncbi.nlm.nih.gov
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