SI
SI
discoversearch

We've detected that you're using an ad content blocking browser plug-in or feature. Ads provide a critical source of revenue to the continued operation of Silicon Investor.  We ask that you disable ad blocking while on Silicon Investor in the best interests of our community.  If you are not using an ad blocker but are still receiving this message, make sure your browser's tracking protection is set to the 'standard' level.
Biotech / Medical : IPIC
IPIC 0.0001000+899.9%Aug 15 3:35 PM EST
 Public ReplyPrvt ReplyMark as Last ReadFilePrevious 10Next 10PreviousNext  
To: Graham Marshman who wrote (608)9/2/1997 4:38:00 PM
From: NeuroInvestment   of 1359
 
An interesting release. There was at least one error of fact and one logical error in Dr. Bowen's release, which seemed largely intended to vindicate Phentermine.
The error of logic: he makes lucid comments regarding the valvular pathology noted in a few patients who have undergone surgery, and the histological similarity to patients suffering from disorders associated with high peripheral serotonin (e.g. carcinoid disorders). He then makes an unfortunate leap: that since high peripheral serotonin levels cause these valvular disorders, the culprit must be the serotonergic drugs, Pondimin and Redux. Dr. Bowen appears to be unaware that these drugs lower peripheral serotonin (i.e. serotonin outside the CNS) and indeed fenfluramine (Pondimin) has been suggested as a possible treatment for carcinoid disorder itself.
The error of fact: Roche has withdrawn its application for Xenical due to FDA concerns about the possibility of breast cancer. Not only is it not going to be available within the next few weeks or months, some estimates are that it will be delayed a year (and that is assuming no further link to breast cancer risk is found).
Dr. Bowen's points about the NEJM taking limited data too far were on target; unfortunately he then replicated the error himself. NeuroInvestment
Report TOU ViolationShare This Post
 Public ReplyPrvt ReplyMark as Last ReadFilePrevious 10Next 10PreviousNext  

HomeMailHotSubjectMarksPeopleMarksKeepersSettings
Terms Of UseContact UsCopyright/IP PolicyPrivacy PolicyAbout UsFAQAdvertise on SI
© 2025 Knight Sac Media.  Data provided by Twelve Data, Alpha Vantage, and CityFALCON News