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Biotech / Medical : TGEN - Targeted Genetics Corporation
TGEN 8.005-1.3%2:22 PM EST

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To: 9wald9 who wrote (432)2/23/2005 11:50:48 PM
From: 9wald9Read Replies (1) of 557
 

Targeted Genetics Announced Preliminary Safety Data From Phase I HIV Vaccine Trial

SEATTLE - PRNewswire-FirstCall - Feb. 22 SEATTLE, Feb. 22 /PRNewswire-FirstCall/ -- Targeted Genetics Corporation today reported preliminary results from a Phase I trial of tgAAC09, an investigational recombinant adeno-associated viral vector (rAAV)-based HIV/AIDS vaccine candidate, enrolling healthy volunteers who are not infected with HIV. The trial is being conducted in Belgium, Germany and India.

The Phase I trial is the first ever to test a rAAV-based vaccine and is primarily designed to evaluate safety and tolerability of the vaccine at escalating dose levels. The study is also designed to evaluate immune responses following vaccination. No safety concerns were identified and the vaccine was well tolerated. In addition, a single administration of the vaccine at the doses evaluated in this initial study did not elicit significant immune responses.... (None had been expected at that dosage as
there had been none seen in animal testing at that dosage per CEO Parker in her 2/23/2005 presentation.)
TGEN closed today at $1.49 no change V 214.3k Market
Cap 121.62m
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