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Biotech / Medical : Cell Therapeutics (CTIC)
CTIC 9.0900.0%Jun 26 5:00 PM EST

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To: former_pgs who wrote (464)2/24/2005 8:50:37 PM
From: zeta1961   of 946
 
the fact that an inactive prodrug is largely excreted as an inactive prodrug simply suggests that this excreted fraction can not contribute to a therapeutic effect. In fact, this fully embraces the premise and theory behind conjugated drugs... :-)

The above is a statement of the obvious..It seems to me that the more productive discussion would not be about Miljenko's past statements about Xyotax since he's not posting in response but to look at the recently published paper to see if it increases our knowledge about the PK/PD and and if it helps us understand the clinical data when it is reported or better yet to 'guesstimate' the data based on what we know now about the progress of the trials...

No??

Zeta
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