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Biotech / Medical : Sangamo Therapeutics, Inc. SGMO
SGMO 0.450-2.5%9:56 AM EST

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To: Ian@SI who wrote (155)4/5/2005 1:00:38 AM
From: tuck   of 368
 
Thanks, though SCID is a small market, and the solution may not be as "general" as Sangamo would have you believe. Cancer, for example, is often thought of as a microscale exercise in Darwinian evolution, in which mutated cells achieve a selective advantage over normal cells and proliferate exponentially.

pubmedcentral.nih.gov

So cancer seems like a tougher task. SCID is low hanging fruit for gene therapy (though it's been tough to pick, even so, as demonstrated by the off target effects resulting in leukemia for several children in a french study that was in fact curing them of SCID), but not certainly not the sweetest one.

Don't get me wrong, it's good news, but until it can show promise in other more common diseases, I'm not going to get too excited.

Cheers, Tuck
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