SCHEDULE OF PURCHASERS 

 

        
Purchaser

--------------------------------------------------------------------------------
    Shares

--------------------------------------------------------------------------------
    Warrants

--------------------------------------------------------------------------------
    Aggregate Purchase
Price

--------------------------------------------------------------------------------
 
Nomura Phase4 Ventures LP
    2,199,010    549,752    $ 14,999,996.97 
ABN AMRO Ventures BV
    366,501    91,625    $ 2,499,994.95 
Oxford Bioscience Partners IV LP
    586,402    146,600    $ 3,999,994.65 
T. Rowe Price New Horizons Fund
    520,000    130,000    $ 3,547,050.00 
Baker Brothers Investments L.P.
    10,097    2,524    $ 68,874.17 
Baker/Tisch Investments, L.P.
    9,388    2,347    $ 64,037.90 
Baker Biotech Fund I, L.P.
    99,064    24,766    $ 675,740.31 
Baker Biotech Fund II, L.P.
    91,191    22,797    $ 622,036.61 
Baker Biotech Fund III, L.P.
    83,461    20,865    $ 569,308.35 
Finsbury Worldwide Pharmaceutical Trust
    359,603    89,900    $ 2,452,941.97 
Biotechnology Value Fund II, L.P.
    181,000    45,250    $ 1,234,646.25 
Biotechnology Value Fund, L.P.
    285,904    71,476    $ 1,950,222.66 
BVF Investments, L.L.C.
    438,000    109,500    $ 2,987,707.50 
Investment 10 LLC
    48,000    12,000    $ 327,420.00 
Total
    5,277,621    1,319,402    $ 35,999,972.29