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Biotech / Medical : SANGUINE CORP. (SGNC)
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To: UnderCover who wrote (5395)5/16/2005 2:17:30 PM
From: UnderCover  Read Replies (1) of 5402
 
Imaging Applications
Perfluorocarbon fluids are being used increasingly in medical diagnostics, specifically ultra-sonic imaging and magnetic resonance imaging (MRI) . For ultra-sound, coronary-scanning applications low boiling perfluorocarbons in microbubbles make excellent contrast imaging agents.

Because the body contains no fluorine the movement of a fluorocarbon through the body is easy to map using magnetic resonance imaging (MRI) attenuating to the 19 fluorine nucleus. 19-fluorine has a sensitivity comparable to 1-hydrogen (proton) and is the only natural isotope. Additionally a perfluorocarbon taken neat and orally can be tracked by the absence of a signal using conventional proton MRI as it contains no hydrogen itself.

Typical compounds Ultra sound - Octafluoropropane, Perfluorobutane. MRI - Perfluorodecalin (can sanguine do this as well, maybe??)

Further Reading: H Carmichael, Chem in Britain, Aug 1998, 30-33. B Cotter et al, in "Ultrasound Contrast Agents" ed. B Soldberg 1997 (ISBN 1-85317-283-9( p31 - 42)
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