[Deep Proteome/Equalizer Bead Technology launched at ASMS]
>>FREMONT, Calif., June 6 /PRNewswire-FirstCall/ -- Ciphergen Biosystems, Inc. (Nasdaq: CIPH - News) today announced the introduction of Deep Proteome(TM) Research Services, making proprietary Equalizer(TM) protein biomarker discovery technology available to scientists for the first time. These services will be preferentially provided to Ciphergen's ProteinChip System customers.
Equalizer technology utilizes novel combinatorial peptide ligand libraries synthesized on beads to compress the dynamic range of protein concentrations by several orders of magnitude while maintaining the diversity and differential levels of expression of the proteome and enabling the detection of trace proteins.
Discovery of low abundance proteins in various proteomes constitutes a major problem in biology research and biomarker discovery. The main options available today to overcome this problem are based on depletion of highly abundant proteins. These methods result in the loss of associated proteins, involve laborious, multi-step methods that are not suited for high throughput, require large sample volumes, and may dilute trace proteins.
Equalizer Beads simultaneously lower the concentration of high abundance proteins and enrich the concentration of low trace proteins without depletion of any specific proteins, in a high throughput manner. When used together with Ciphergen's new, automated MultiSelect(TM) protein profiling technology, trace protein detection and total protein count are dramatically improved.
"The Equalizer(TM) technology has been received with great excitement by the scientific community. We are convinced that this technology is a major breakthrough in proteomics. Our Deep Proteome Research Services will enable scientists to look at low abundance proteins in various biological samples and significantly improve their biomarker discovery power," commented Martin Verhoef, President of Ciphergen's Biosystems Division.<<
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Cheers, Tuck |
