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Biotech / Medical : momo-T/FIF

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To: tuck who wrote (2934)	8/25/2005 10:44:56 PM
From: scaram(o)uche	Read Replies (2) of 12215

Your question brought out fun commentary. Thanks. Polymorphism within the MHC is extreme. I was lucky as heck. For decades, the lab of George Snell and numerous other labs which recognized the brilliance in his approach had focused on dissecting the MHC with polyclonal antisera. It was a rush to isolate antibodies which recognized an epitope that Snell et al. (in the very large sense, as he cast a long shadow........ a frigging gentleman and unassuming guy, I might add) had characterized with a titer of 1:20 or sumthin (and they busted their butt to get that!), and find that you could ten-fold dilute seven times before starting your assay. It was a bigger rush to discover that one out of two antibodies found something that a score of the best had missed for years. Antibodies are fun. Wholesome, good for the entire family. I'm moving, folks. Gonna be spotty in the next week. Small-cap, big-science....... great summer. Phenomenal summer. Heaven. Best, all! Rick

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