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Biotech / Medical : NTII - Miscellaneous

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Mar 7 3:00 PM EST

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From: John McCarthy	10/25/2005 9:17:52 AM
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2005 - Memantine and Phantom Pain October - 2005 THE GOOD NEWS - YOU CAN LEARN NOT TO FEEL THE BURN Thankfully, like other things you've learnt, you can sometimes "forget" chronic pain. Pathological forms of learning, also involved in problems such as addictions, seem to be especially hard to undo, but there's some evidence they can be halted or even reversed. In one recent study, people who had lost a limb immediately took Memantine, a drug that blocks memory-encoding receptors. Usually, more than two-thirds of amputees have phantom pain, but only 20 per cent of those treated with the medication developed it, says Herta Flor. But the drug doesn't have the same effect once phantom pain has set in. Flor found that prosthetic limbs can help amputees unlearn their aches. Imaging studies show that with a functional prosthetic, the brain begins to respond as though the replacement limb were a part of the body. This semblance of normality dampens the errant pain signals. news.independent.co.uk

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