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Biotech / Medical : Rigel Pharmaceuticals, Inc. (RIGL)
RIGL 37.87+33.8%Nov 5 3:59 PM EST

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From: kenhott12/1/2005 11:41:44 AM
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Just looking around after the news this morning. Someone in the know should speak up since I don't. The obvious question is what happened. But the market is not wrong here to hit the stock hard since the comparator worked but the drug did not. That tells me that RIGL didn't just have a bad luck bum trial. For me, that calls into question the target syk. Which links to the PFE deal in asthma and the RA drug, all targeting syk. HepC is back to the drawing board for another turn around. R763 targets aurora which is a balance act since R763 will knock off fast growing normal cells in the body if it works. Can aurora be tuned just right? Of course MRK and Serono are betting that it is possible.

Maybe the conference call will help to fill in some more info.
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