Zonagen (zona) - good buy? Message Board

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Biotech / Medical : Zonagen (zona) - good buy?

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To: Dauntless who wrote (546)	9/15/1997 12:56:00 PM
From: Tokyo VD	of 7041

Short Zonagen? Maybe. The data that everyone compares Zonagen to is the Vivus and Pharmacia-UpJohn studies. In these studies, men who suffer from severe ED benefitted from the treatment in 65% and 83%, respectively. But, if you looked at it on an intent-to-treat basis, the numbers fall to roughly 45% and 65%, respectively. You then take the Zonagen data, which measures an entirely different class of patients (mild to moderate), ask them to respond to a subjective questionnaire (IIEF), and then try to "emphasize" the data that shows better efficacy (40% vs. 17% placebo in one study, while the other showed 34% vs. 21% placebo). Even if this does get approved, how does a partner price the product competitively to Pfizer's sildenafil?

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